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Proteomic analysis of s-acylated proteins in human retinal pigment epithelial cells and the role of palmitoylation of Niemann-Pick type C1 protein in cholesterol transport

Palmitoylation is a dynamic process that regulates the activity of the modified proteins. Retinal pigment epithelial (RPE) cells play pivotal roles in the visual cycle and maintaining healthy photoreceptor cells. Dysfunctional RPE cells are often associated with degenerative retinal diseases. The ai...

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Detalles Bibliográficos
Autores principales: Li, Jia Kai, Rao, Yu Qing, Koh, Siew Kwan, Zhao, Peiquan, Zhou, Lei, Li, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576141/
https://www.ncbi.nlm.nih.gov/pubmed/36262888
http://dx.doi.org/10.3389/fnagi.2022.965943