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Genetically predicted high IGF-1 levels showed protective effects on COVID-19 susceptibility and hospitalization: a Mendelian randomisation study with data from 60 studies across 25 countries

BACKGROUND: Epidemiological studies observed gender differences in COVID-19 outcomes, however, whether sex hormone plays a causal in COVID-19 risk remains unclear. This study aimed to examine associations of sex hormone, sex hormones-binding globulin (SHBG), insulin-like growth factor-1 (IGF-1), and...

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Detalles Bibliográficos
Autores principales: Li, Xinxuan, Zhou, Yajing, Yuan, Shuai, Zhou, Xuan, Wang, Lijuan, Sun, Jing, Yu, Lili, Zhu, Jinghan, Zhang, Han, Yang, Nan, Dai, Shuhui, Song, Peige, Larsson, Susanna C, Theodoratou, Evropi, Zhu, Yimin, Li, Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576268/
https://www.ncbi.nlm.nih.gov/pubmed/36250974
http://dx.doi.org/10.7554/eLife.79720