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Association of Pace of Aging Measured by Blood-Based DNA Methylation With Age-Related Cognitive Impairment and Dementia

BACKGROUND AND OBJECTIVES: DNA methylation algorithms are increasingly used to estimate biological aging; however, how these proposed measures of whole-organism biological aging relate to aging in the brain is not known. We used data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) a...

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Detalles Bibliográficos
Autores principales: Sugden, Karen, Caspi, Avshalom, Elliott, Maxwell L., Bourassa, Kyle J., Chamarti, Kartik, Corcoran, David L., Hariri, Ahmad R., Houts, Renate M., Kothari, Meeraj, Kritchevsky, Stephen, Kuchel, George A., Mill, Jonathan S., Williams, Benjamin S., Belsky, Daniel W., Moffitt, Terrie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576288/
https://www.ncbi.nlm.nih.gov/pubmed/35794023
http://dx.doi.org/10.1212/WNL.0000000000200898