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Irisin Promotes Osteogenesis by Modulating Oxidative Stress and Mitophagy through SIRT3 Signaling under Diabetic Conditions

Advanced glycation end products (AGEs) accumulate in the bone tissue of patients with diabetes mellitus, resulting in oxidative stress, poor bone healing, or regeneration. Irisin, a novel exercise-induced myokine, is involved in the regulation of bone metabolism. However, the effects of irisin on ad...

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Detalles Bibliográficos
Autores principales: Li, Guangyue, Jian, Zixiang, Wang, He, Xu, Ling, Zhang, Tingwei, Song, Jinlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576424/
https://www.ncbi.nlm.nih.gov/pubmed/36262283
http://dx.doi.org/10.1155/2022/3319056