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Combination of Tumor Mutational Burden and DNA Damage Repair Gene Mutations with Stromal/Immune Scores Improved Prognosis Stratification in Patients with Lung Adenocarcinoma

BACKGROUND: Both the tumor environment and the genomic landscape of lung cancer may shape patient responses to treatments, including immunotherapy, but their joint impacts on lung adenocarcinoma (LUAD) prognosis are underexplored. METHODS: RNA sequencing data and whole-exome sequencing results were...

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Detalles Bibliográficos
Autores principales: Wu, Dongping, Huang, Lingjuan, Mao, Jiwei, Liu, Jianjiang, Ye, Wanli, Xu, Jun, Zhong, Wangyan, Zhang, Xiaoyu, Ying, Shenpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576425/
https://www.ncbi.nlm.nih.gov/pubmed/36262349
http://dx.doi.org/10.1155/2022/6407344