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Combination of Tumor Mutational Burden and DNA Damage Repair Gene Mutations with Stromal/Immune Scores Improved Prognosis Stratification in Patients with Lung Adenocarcinoma
BACKGROUND: Both the tumor environment and the genomic landscape of lung cancer may shape patient responses to treatments, including immunotherapy, but their joint impacts on lung adenocarcinoma (LUAD) prognosis are underexplored. METHODS: RNA sequencing data and whole-exome sequencing results were...
Autores principales: | Wu, Dongping, Huang, Lingjuan, Mao, Jiwei, Liu, Jianjiang, Ye, Wanli, Xu, Jun, Zhong, Wangyan, Zhang, Xiaoyu, Ying, Shenpeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576425/ https://www.ncbi.nlm.nih.gov/pubmed/36262349 http://dx.doi.org/10.1155/2022/6407344 |
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