In Silico Identification of New Anti-SARS-CoV-2 Main Protease (M(pro)) Molecules with Pharmacokinetic Properties from Natural Sources Using Molecular Dynamics (MD) Simulations and Hierarchical Virtual Screening

Infectious agents such as SARS-CoV, MERS-CoV, and SARS-CoV-2 have emerged in recent years causing epidemics with high mortality rates. The quick development of novel therapeutic compounds is required in the fight against such pathogenic agents. Unfortunately, the traditional drug development methods...

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Detalles Bibliográficos
Autores principales: Onyango, Harrison, Odhiambo, Patrick, Angwenyi, David, Okoth, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576439/
https://www.ncbi.nlm.nih.gov/pubmed/36263438
http://dx.doi.org/10.1155/2022/3697498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576439/
https://www.ncbi.nlm.nih.gov/pubmed/36263438
http://dx.doi.org/10.1155/2022/3697498

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