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C3G down-regulation enhances pro-migratory and stemness properties of oval cells by promoting an epithelial-mesenchymal-like process

Previous data indicate that C3G (RapGEF1) main isoform is highly expressed in liver progenitor cells (or oval cells) compared to adult mature hepatocytes, suggesting it may play an important role in oval cell biology. Hence, we have explored C3G function in the regulation of oval cell properties by...

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Detalles Bibliográficos
Autores principales: Palao, Nerea, Sequera, Celia, Cuesta, Ángel M, Baquero, Cristina, Bragado, Paloma, Gutierrez-Uzquiza, Alvaro, Sánchez, Aránzazu, Guerrero, Carmen, Porras, Almudena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576514/
https://www.ncbi.nlm.nih.gov/pubmed/36263169
http://dx.doi.org/10.7150/ijbs.73192