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Small molecule quercetin binds MALAT1 triplex and modulates its cellular function
The triple-helix structure at the 3′ end of metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), a long non-coding RNA, has been considered to be a target for modulating the oncogenic functions of MALAT1. This study examines the binding of quercetin—a known triplex binding molecule—to th...
Autores principales: | Rakheja, Isha, Ansari, Asgar Hussain, Ray, Arjun, Chandra Joshi, Dheeraj, Maiti, Souvik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576543/ https://www.ncbi.nlm.nih.gov/pubmed/36284512 http://dx.doi.org/10.1016/j.omtn.2022.09.016 |
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