Exosomal HMGA2 protein from EBV-positive NPC cells destroys vascular endothelial barriers and induces endothelial-to-mesenchymal transition to promote metastasis

Increased vascular permeability facilitates metastasis. Cancer-secreted exosomes are emerging mediators of cancer-host crosstalk. Epstein-Barr virus (EBV), identified as the first human tumor-associated virus, plays a crucial role in metastatic tumors, especially in nasopharyngeal carcinoma (NPC). T...

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Detalles Bibliográficos
Autores principales: Li, Deng-Ke, Chen, Xing-Rui, Wang, Li-Na, Wang, Jia-Hong, Li, Ji-Ke, Zhou, Zi-Ying, Li, Xin, Cai, Lin-Bo, Zhong, Shui-Sheng, Zhang, Jing-Jing, Zeng, Yu-Mei, Zhang, Qian-Bing, Fu, Xiao-Yan, Lyu, Xiao-Ming, Li, Min-Ying, Huang, Zhong-Xi, Yao, Kai-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576596/
https://www.ncbi.nlm.nih.gov/pubmed/35388172
http://dx.doi.org/10.1038/s41417-022-00453-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576596/
https://www.ncbi.nlm.nih.gov/pubmed/35388172
http://dx.doi.org/10.1038/s41417-022-00453-6

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