m(6)A demethylase ALKBH5 promotes tumor cell proliferation by destabilizing IGF2BPs target genes and worsens the prognosis of patients with non-small-cell lung cancer

The modification of N(6)-methyladenosine (m(6)A) in RNA and its eraser ALKBH5, an m(6)A demethylase, play an important role across various steps of human carcinogenesis. However, the involvement of ALKBH5 in non-small-cell lung cancer (NSCLC) development remains to be completely elucidated. The curr...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsuchiya, Kazuo, Yoshimura, Katsuhiro, Iwashita, Yuji, Inoue, Yusuke, Ohta, Tsutomu, Watanabe, Hirofumi, Yamada, Hidetaka, Kawase, Akikazu, Tanahashi, Masayuki, Ogawa, Hiroshi, Funai, Kazuhito, Shinmura, Kazuya, Suda, Takafumi, Sugimura, Haruhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576599/
https://www.ncbi.nlm.nih.gov/pubmed/35318440
http://dx.doi.org/10.1038/s41417-022-00451-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576599/
https://www.ncbi.nlm.nih.gov/pubmed/35318440
http://dx.doi.org/10.1038/s41417-022-00451-8

Ejemplares similares