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m(6)A demethylase ALKBH5 promotes tumor cell proliferation by destabilizing IGF2BPs target genes and worsens the prognosis of patients with non-small-cell lung cancer

The modification of N(6)-methyladenosine (m(6)A) in RNA and its eraser ALKBH5, an m(6)A demethylase, play an important role across various steps of human carcinogenesis. However, the involvement of ALKBH5 in non-small-cell lung cancer (NSCLC) development remains to be completely elucidated. The curr...

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Detalles Bibliográficos
Autores principales:	Tsuchiya, Kazuo, Yoshimura, Katsuhiro, Iwashita, Yuji, Inoue, Yusuke, Ohta, Tsutomu, Watanabe, Hirofumi, Yamada, Hidetaka, Kawase, Akikazu, Tanahashi, Masayuki, Ogawa, Hiroshi, Funai, Kazuhito, Shinmura, Kazuya, Suda, Takafumi, Sugimura, Haruhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576599/ https://www.ncbi.nlm.nih.gov/pubmed/35318440 http://dx.doi.org/10.1038/s41417-022-00451-8

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