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Activated Src requires Cadherin-11, Rac, and gp130 for Stat3 activation and survival of mouse Balb/c3T3 fibroblasts

We previously demonstrated that engagement of cadherins, cell to cell adhesion molecules, triggers a dramatic increase in levels and activity of the Rac/Cdc42 small GTPases, which is followed by secretion of IL6 family cytokines and activation of their common receptor, gp130, in an autocrine manner....

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Detalles Bibliográficos
Autores principales: Adan, Hanad, Guy, Stephanie, Arulanandam, Rozanne, Geletu, Mulu, Daniel, Juliet, Raptis, Leda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576600/
https://www.ncbi.nlm.nih.gov/pubmed/35411090
http://dx.doi.org/10.1038/s41417-022-00462-5