Specificity of oligonucleotide gene therapy (OGT) agents

Oligonucleotide gene therapy (OGT) agents (e. g. antisense, deoxyribozymes, siRNA and CRISPR/Cas) are promising therapeutic tools. Despite extensive efforts, only few OGT drugs have been approved for clinical use. Besides the problem of efficient delivery to targeted cells, hybridization specificity...

Descripción completa

Detalles Bibliográficos
Autores principales: Nedorezova, Daria D., Dubovichenko, Mikhail V., Belyaeva, Ekaterina P., Grigorieva, Ekaterina D., Peresadina, Arina V., Kolpashchikov, Dmitry M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576606/
https://www.ncbi.nlm.nih.gov/pubmed/36276652
http://dx.doi.org/10.7150/thno.77830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576606/
https://www.ncbi.nlm.nih.gov/pubmed/36276652
http://dx.doi.org/10.7150/thno.77830

Ejemplares similares