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ERK inactivation enhances stemness of NSCLC cells via promoting Slug-mediated epithelial-to-mesenchymal transition

Rationale: The mitogen-activated protein kinase pathway (MAPK) is one of the major cancer-driving pathways found in non-small cell lung cancer (NSCLC) patients. ERK inhibitors (ERKi) have been shown to be effective in NSCLC patients with MAPK pathway mutations. However, like other MAPK inhibitors, E...

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Detalles Bibliográficos
Autores principales: Cai, Shurui, Li, Na, Bai, Xuetao, Liu, Lu, Banerjee, Ananya, Lavudi, Kousalya, Zhang, Xiaoli, Zhao, Jihe, Venere, Monica, Duan, Wenrui, Zhang, Junran, Welliver, Meng X., He, Kai, Wang, Qi-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576621/
https://www.ncbi.nlm.nih.gov/pubmed/36276640
http://dx.doi.org/10.7150/thno.73099