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How pragmatic are randomized trials of remdesivir and favipiravir for in-hospital treatment of COVID-19: a descriptive methodological review of trial design using the PRECIS-2 framework

OBJECTIVES: To review the pragmatism of published randomized trials of remdesivir and favipiravir based on the Pragmatic-Explanatory Continuum Indicator Summary (PRECIS-2) framework. STUDY DESIGN AND SETTING: Ten eligible trials were identified from an existing comprehensive living review and were e...

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Detalles Bibliográficos
Autores principales: Sharma, Tanmay, Qamar, Intisar, Zwarenstein, Merrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576695/
https://www.ncbi.nlm.nih.gov/pubmed/36265553
http://dx.doi.org/10.1016/j.jclinepi.2022.10.013