Host adaptive mutations in the 2009 H1N1 pandemic influenza A virus PA gene regulate translation efficiency of viral mRNAs via GRSF1

Avian species are the major natural reservoir from which pandemic influenza A viruses can be introduced to humans. Avian influenza A virus genes, including the three viral polymerase genes, PA, PB1 and PB2, require host-adaptive mutations to allow for viral replication and transmission in humans. Pr...

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Detalles Bibliográficos
Autores principales: Lutz, Michael, Schmierer, Jordana, Takimoto, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576711/
https://www.ncbi.nlm.nih.gov/pubmed/36253464
http://dx.doi.org/10.1038/s42003-022-04082-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576711/
https://www.ncbi.nlm.nih.gov/pubmed/36253464
http://dx.doi.org/10.1038/s42003-022-04082-5

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