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Screening of the siGPCR library in combination with cisplatin against lung cancers

The screening of siRNAs targeting 390 human G protein-coupled receptors (GPCRs) was multiplexed in combination with cisplatin against lung cancer cells. While the cell viability measure hardly captured the anticancer effect of siGPCRs, the direct cell count revealed the anticancer potential of diver...

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Detalles Bibliográficos
Autores principales: Kim, Youngju, Lee, Jieun, Jeong, Sumin, Kim, Woo-Young, Jeong, Euna, Yoon, Sukjoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576725/
https://www.ncbi.nlm.nih.gov/pubmed/36253428
http://dx.doi.org/10.1038/s41598-022-21063-0