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Bone marrow mesenchymal stem cell-derived exosomal miR-21a-5p alleviates renal fibrosis by attenuating glycolysis by targeting PFKM

Renal fibrosis is a common pathological feature and outcome of almost all chronic kidney diseases, and it is characterized by metabolic reprogramming toward aerobic glycolysis. Mesenchymal stem cell-derived exosomes (MSC-Exos) have been proposed as a promising therapeutic approach for renal fibrosis...

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Detalles Bibliográficos
Autores principales: Xu, Shihao, Cheuk, Yin Celeste, Jia, Yichen, Chen, Tian, Chen, Juntao, Luo, Yongsheng, Cao, Yirui, Guo, Jingjing, Dong, Lijun, Zhang, Yi, Shi, Yi, Rong, Ruiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576726/
https://www.ncbi.nlm.nih.gov/pubmed/36253358
http://dx.doi.org/10.1038/s41419-022-05305-7