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Bone marrow mesenchymal stem cell-derived exosomal miR-21a-5p alleviates renal fibrosis by attenuating glycolysis by targeting PFKM
Renal fibrosis is a common pathological feature and outcome of almost all chronic kidney diseases, and it is characterized by metabolic reprogramming toward aerobic glycolysis. Mesenchymal stem cell-derived exosomes (MSC-Exos) have been proposed as a promising therapeutic approach for renal fibrosis...
Autores principales: | Xu, Shihao, Cheuk, Yin Celeste, Jia, Yichen, Chen, Tian, Chen, Juntao, Luo, Yongsheng, Cao, Yirui, Guo, Jingjing, Dong, Lijun, Zhang, Yi, Shi, Yi, Rong, Ruiming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576726/ https://www.ncbi.nlm.nih.gov/pubmed/36253358 http://dx.doi.org/10.1038/s41419-022-05305-7 |
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