Brain milieu induces early microglial maturation through the BAX-Notch axis

Microglia are derived from primitive myeloid cells and gain their early identity in the embryonic brains. However, the mechanism by which the brain milieu confers microglial maturation signature remains elusive. Here, we demonstrate that the bax(cq55) zebrafish and Bax(tm1Sjk) mouse embryos exhibit...

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Detalles Bibliográficos
Autores principales: Zhao, Fangying, He, Jiangyong, Tang, Jun, Cui, Nianfei, Shi, Yanyan, Li, Zhifan, Liu, Shengnan, Wang, Yazhou, Ma, Ming, Zhao, Congjian, Luo, Lingfei, Li, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576735/
https://www.ncbi.nlm.nih.gov/pubmed/36253375
http://dx.doi.org/10.1038/s41467-022-33836-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576735/
https://www.ncbi.nlm.nih.gov/pubmed/36253375
http://dx.doi.org/10.1038/s41467-022-33836-2

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