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Actin polymerization promotes invagination of flat clathrin-coated lattices in mammalian cells by pushing at lattice edges

Clathrin-mediated endocytosis (CME) requires energy input from actin polymerization in mechanically challenging conditions. The roles of actin in CME are poorly understood due to inadequate knowledge of actin organization at clathrin-coated structures (CCSs). Using platinum replica electron microsco...

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Detalles Bibliográficos
Autores principales: Yang, Changsong, Colosi, Patricia, Hugelier, Siewert, Zabezhinsky, Daniel, Lakadamyali, Melike, Svitkina, Tatyana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576739/
https://www.ncbi.nlm.nih.gov/pubmed/36253374
http://dx.doi.org/10.1038/s41467-022-33852-2