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Actin polymerization promotes invagination of flat clathrin-coated lattices in mammalian cells by pushing at lattice edges
Clathrin-mediated endocytosis (CME) requires energy input from actin polymerization in mechanically challenging conditions. The roles of actin in CME are poorly understood due to inadequate knowledge of actin organization at clathrin-coated structures (CCSs). Using platinum replica electron microsco...
Autores principales: | Yang, Changsong, Colosi, Patricia, Hugelier, Siewert, Zabezhinsky, Daniel, Lakadamyali, Melike, Svitkina, Tatyana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576739/ https://www.ncbi.nlm.nih.gov/pubmed/36253374 http://dx.doi.org/10.1038/s41467-022-33852-2 |
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