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Angiotensin II type-1 receptor-associated protein interacts with transferrin receptor-1 and promotes its internalization

Kidney fibrosis is a common pathway that leads to chronic kidney disease. Angiotensin II type-1 receptor (AT1R)-associated protein (ATRAP) was originally identified as an AT1R-binding protein. Previously, we reported that systemic knockout of ATRAP exacerbates kidney fibrosis in aged mice. Although...

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Detalles Bibliográficos
Autores principales: Abe, Eriko, Yamashita, Akio, Hirota, Keigo, Yamaji, Takahiro, Azushima, Kengo, Urate, Shingo, Suzuki, Toru, Tanaka, Shohei, Taguchi, Shinya, Tsukamoto, Shunichiro, Uehara, Tatsuki, Wakui, Hiromichi, Tamura, Kouichi, Takahashi, Hidehisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576747/
https://www.ncbi.nlm.nih.gov/pubmed/36253401
http://dx.doi.org/10.1038/s41598-022-22343-5