Comprehensive single cell analysis of pandemic influenza A virus infection in the human airways uncovers cell-type specific host transcriptional signatures relevant for disease progression and pathogenesis

The respiratory epithelium constitutes the first line of defense against invading respiratory pathogens, such as the 2009 pandemic strain of influenza A virus (IAV, H1N1pdm09), and plays a crucial role in the host antiviral response to infection. Despite its importance, however, it remains unknown h...

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Detalles Bibliográficos
Autores principales: Kelly, Jenna N., Laloli, Laura, V’kovski, Philip, Holwerda, Melle, Portmann, Jasmine, Thiel, Volker, Dijkman, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576848/
https://www.ncbi.nlm.nih.gov/pubmed/36268025
http://dx.doi.org/10.3389/fimmu.2022.978824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576848/
https://www.ncbi.nlm.nih.gov/pubmed/36268025
http://dx.doi.org/10.3389/fimmu.2022.978824

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