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Genetic regulation of newborn telomere length is mediated and modified by DNA methylation

Telomere length at birth determines later life telomere length and potentially predicts ageing-related diseases. However, the genetic and epigenetic settings of telomere length in newborns have not been analyzed. In addition, no study yet has reported how the interplay between genetic variants and g...

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Detalles Bibliográficos
Autores principales: Wang, Congrong, Alfano, Rossella, Reimann, Brigitte, Hogervorst, Janneke, Bustamante, Mariona, De Vivo, Immaculata, Plusquin, Michelle, Nawrot, Tim S., Martens, Dries S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576874/
https://www.ncbi.nlm.nih.gov/pubmed/36267401
http://dx.doi.org/10.3389/fgene.2022.934277