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Microarray-guided evaluation of the frequency, B-cell origins, and selectivity of human glycan-binding antibodies reveals new insights and novel antibodies

The immune system produces a diverse collection of antiglycan antibodies that are critical for host defense. At present, however, we know very little about the binding properties, origins, and sequences of these antibodies because of a lack of access to a variety of defined individual antibodies. To...

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Detalles Bibliográficos
Autores principales: Temme, J. Sebastian, Crainic, Jennifer A., Walker, Laura M., Yang, Weizhun, Tan, Zibin, Huang, Xuefei, Gildersleeve, Jeffrey C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576894/
https://www.ncbi.nlm.nih.gov/pubmed/36087840
http://dx.doi.org/10.1016/j.jbc.2022.102468