Quantitative Nuclear Histomorphometry Predicts Molecular Subtype and Clinical Outcome in Medulloblastomas: Preliminary Findings

Molecular subtypes of medulloblastoma [Sonic Hedgehog (SHH), Wingless/INT (WNT), Group 3, and Group 4] are defined by common patterns of gene expression. These differential gene expression patterns appear to result in different histomorphology and prognosis. Quantitative histomorphometry is a well-k...

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Detalles Bibliográficos
Autores principales: Whitney, Jon, Dollinger, Liisa, Tamrazi, Benita, Hawes, Debra, Couce, Marta, Marcheque, Julia, Judkins, Alexander, Margol, Ashley, Madabhushi, Anant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576985/
https://www.ncbi.nlm.nih.gov/pubmed/36268104
http://dx.doi.org/10.1016/j.jpi.2022.100090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576985/
https://www.ncbi.nlm.nih.gov/pubmed/36268104
http://dx.doi.org/10.1016/j.jpi.2022.100090

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