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Quantitative Nuclear Histomorphometry Predicts Molecular Subtype and Clinical Outcome in Medulloblastomas: Preliminary Findings
Molecular subtypes of medulloblastoma [Sonic Hedgehog (SHH), Wingless/INT (WNT), Group 3, and Group 4] are defined by common patterns of gene expression. These differential gene expression patterns appear to result in different histomorphology and prognosis. Quantitative histomorphometry is a well-k...
Autores principales: | Whitney, Jon, Dollinger, Liisa, Tamrazi, Benita, Hawes, Debra, Couce, Marta, Marcheque, Julia, Judkins, Alexander, Margol, Ashley, Madabhushi, Anant |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576985/ https://www.ncbi.nlm.nih.gov/pubmed/36268104 http://dx.doi.org/10.1016/j.jpi.2022.100090 |
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