Spatial heterogeneity and organization of tumor mutation burden with immune infiltrates within tumors based on whole slide images correlated with patient survival in bladder cancer

BACKGROUND: High tumor mutation burden (TMB-H) could result in an increased number of neoepitopes from somatic mutations expressed by a patient’s own tumor cell which can be recognized and targeted by neighboring tumor-infiltrating lymphocytes (TILs). Deeper understanding of spatial heterogeneity an...

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Detalles Bibliográficos
Autores principales: Xu, Hongming, Clemenceau, Jean René, Park, Sunho, Choi, Jinhwan, Lee, Sung Hak, Hwang, Tae Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577053/
https://www.ncbi.nlm.nih.gov/pubmed/36268064
http://dx.doi.org/10.1016/j.jpi.2022.100105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577053/
https://www.ncbi.nlm.nih.gov/pubmed/36268064
http://dx.doi.org/10.1016/j.jpi.2022.100105

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