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Formulation of ciprofloxacin-loaded oral self-emulsifying drug delivery system to improve the pharmacokinetics and antibacterial activity

This study aims to increase the aqueous solubility of ciprofloxacin (CPN) to improve oral bioavailability. This was carried out by formulating a stable formulation of the Self-Emulsifying Drug Delivery System (SEDDS) using various ratios of lipid/oil, surfactant, and co-surfactant. A pseudo-ternary...

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Detalles Bibliográficos
Autores principales: Asghar, Asghar Ali, Akhlaq, Muhammad, Jalil, Aamir, Azad, Abul Kalam, Asghar, Junaid, Adeel, Muhammad, Albadrani, Ghadeer M., Al-Doaiss, Amin A., Kamel, Mohamed, Altyar, Ahmed E., Abdel-Daim, Mohamed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577179/
https://www.ncbi.nlm.nih.gov/pubmed/36267282
http://dx.doi.org/10.3389/fphar.2022.967106