Epigenetic modifier Kdm6a/Utx controls the specification of hypothalamic neuronal subtypes in a sex-dependent manner

Kdm6a is an X-chromosome-linked H3K27me2/3 demethylase that promotes chromatin accessibility and gene transcription and is critical for tissue/cell-specific differentiation. Previous results showed higher Kdm6a levels in XX than in XY hypothalamic neurons and a female-specific requirement for Kdm6a...

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Detalles Bibliográficos
Autores principales: Cabrera Zapata, Lucas E., Cambiasso, María Julia, Arevalo, Maria Angeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577230/
https://www.ncbi.nlm.nih.gov/pubmed/36268511
http://dx.doi.org/10.3389/fcell.2022.937875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577230/
https://www.ncbi.nlm.nih.gov/pubmed/36268511
http://dx.doi.org/10.3389/fcell.2022.937875

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