Novel saccharin analogs as promising antibacterial and anticancer agents: synthesis, DFT, POM analysis, molecular docking, molecular dynamic simulations, and cell-based assay

Saccharine is a pharmacologically significant active scaffold for various biological activities, including antibacterial and anticancer activities. Herein, saccharinyl hydrazide (1) was synthesized and converted into 2-[(2Z)-2-(1,1-dioxo-1,2-dihydro-3H-1λ(6),2- benzothiazole-3-ylidene) hydrazinyl] a...

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Detalles Bibliográficos
Autores principales: Abdellattif, Magda H., Elkamhawy, Ahmed, Hagar, Mohamed, Hadda, Taibi Ben, Shehab, Wesam S., Mansy, Wael, Belal, Amany, Arief, M. M. H., Hussien, Mostafa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577234/
https://www.ncbi.nlm.nih.gov/pubmed/36267293
http://dx.doi.org/10.3389/fphar.2022.958379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577234/
https://www.ncbi.nlm.nih.gov/pubmed/36267293
http://dx.doi.org/10.3389/fphar.2022.958379

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