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CDK12 orchestrates super‐enhancer‐associated CCDC137 transcription to direct hepatic metastasis in colorectal cancer

BACKGROUND: Hepatic metastasis is the primary and direct cause of death in individuals with colorectal cancer (CRC) attribute to lack of effective therapeutic targets. The present study aimed to identify potential druggable candidate targets for patients with liver metastatic CRC. METHODS: The trans...

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Detalles Bibliográficos
Autores principales: Dai, Wei, Wu, Junhong, Peng, Xiaopeng, Hou, Wen, Huang, Hao, Cheng, Qilai, Liu, Zhiping, Luyten, Walter, Schoofs, Liliane, Zhou, Jingfeng, Liu, Shenglan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577262/
https://www.ncbi.nlm.nih.gov/pubmed/36254394
http://dx.doi.org/10.1002/ctm2.1087