Identification of novel natural drug candidates against BRAF mutated carcinoma; An integrative in-silico structure-based pharmacophore modeling and virtual screening process

The BRAF gene is responsible for transferring signals from outside of the cell to inside of the nucleus by converting a protein namely B-Raf through the RAS/MAPK pathway. This pathway contribute to cell division, proliferation, migration, and apoptotic cell death of human and animal. Mutation in thi...

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Detalles Bibliográficos
Autores principales: Dain Md Opo, F. A., Alsaiari, Ahad Amer, Rahman Molla, Mohammad Habibur, Ahmed Sumon, Md Afsar, Yaghmour, Khaled A., Ahammad, Foysal, Mohammad, Farhan, Simal-Gandara, Jesus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577413/
https://www.ncbi.nlm.nih.gov/pubmed/36267655
http://dx.doi.org/10.3389/fchem.2022.986376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577413/
https://www.ncbi.nlm.nih.gov/pubmed/36267655
http://dx.doi.org/10.3389/fchem.2022.986376

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