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GATA2 haploinsufficient patients lack innate lymphoid cells that arise after hematopoietic cell transplantation

Innate lymphoid cells (ILC) are important barrier tissue immune regulators. They play a pivotal role in early non-specific protection against infiltrating pathogens, regulation of epithelial integrity, suppression of pro-inflammatory immune responses and shaping the intestinal microbiota. GATA2 hapl...

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Detalles Bibliográficos
Autores principales: van Lier, Y. F., Krabbendam, L., Haverkate, N. J. E., Zeerleder, S. S., Rutten, C. E., Blom, B., Spits, H., Hazenberg, M. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577555/
https://www.ncbi.nlm.nih.gov/pubmed/36268026
http://dx.doi.org/10.3389/fimmu.2022.1020590