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Pathologic light chain amyloidosis oligomer detection in urinary extracellular vesicles as a diagnostic tool for response and progression of disease

Light Chain (AL) Amyloidosis is a plasma cell dyscrasia producing amyloidogenic light chains (LC) that misfold and form amyloid deposits that cause damage in vital organs, primarily the heart and kidneys. Urinary extracellular vesicles (uEVs) are nanoparticles produced by renal epithelial cells thro...

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Detalles Bibliográficos
Autores principales: Cooper, Shawna A., Dick, Christopher J., Misra, Pinaki, Leung, Nelson, Schinstock, Carrie A., Ramirez-Alvarado, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577681/
https://www.ncbi.nlm.nih.gov/pubmed/36267963
http://dx.doi.org/10.3389/fonc.2022.978198