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Sources of bias for single-arm phase II cancer clinical trials
A phase II trial is conducted to investigate if an experimental therapy is efficacious enough to proceed to a large-scale phase III trial or not. In spite of the fast progress in design and analysis methods, single-arm two-stage design is still the most popular for phase II cancer clinical trials. I...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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AME Publishing Company
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577758/ https://www.ncbi.nlm.nih.gov/pubmed/36267796 http://dx.doi.org/10.21037/atm-21-6808 |