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Molecular mechanism of CD163(+) tumor-associated macrophage (TAM)-derived exosome-induced cisplatin resistance in ovarian cancer ascites

BACKGROUND: Studies have found that tumor-associated macrophages (TAMs) in the malignant ascites of patients with serous ovarian cancer exhibit a mixed polarization phenotype and highly variable expression of the surface marker CD163. The exosomes secreted by mesenchymal cells can be taken up by tum...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaohui, Wang, Jiapo, Liu, Na, Wu, Weimin, Li, Hong, Chen, Jinhong, Guo, Xiaoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577761/
https://www.ncbi.nlm.nih.gov/pubmed/36267748
http://dx.doi.org/10.21037/atm-22-4267