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Successful re-challenge of dabrafenib-trametinib combination therapy in advanced BRAF(V600E)-mutant non-small cell lung cancer after previous cytotoxic chemotherapy, targeted therapy, and immunotherapy: a case report
BACKGROUND: Patients with v-raf murine sarcoma viral oncogene homolog B1 (BRAF)(V600E)-mutant non-small cell lung cancer (NSCLC) benefit from treatment with a combination of BRAF and mitogen-activated protein kinase (MEK) inhibitors, but resistance and disease progression develop in most patients. P...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577789/ https://www.ncbi.nlm.nih.gov/pubmed/36267742 http://dx.doi.org/10.21037/atm-22-3887 |