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MiR-539-3p impairs osteogenesis by suppressing Wnt interaction with LRP-6 co-receptor and subsequent inhibition of Akap-3 signaling pathway

X-linked hypophosphatemia (XLH), an inheritable form of rickets is caused due to mutation in Phex gene. Several factors are linked to the disease’s aetiology, including non-coding RNA molecules (miRNAs), which are key post-transcriptional regulators of gene expression and play a significant role in...

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Detalles Bibliográficos
Autores principales: Tripathi, Alok, John, Aijaz A., Kumar, Deepak, Kaushal, Saurabh Kumar, Singh, Devendra Pratap, Husain, Nazim, Sarkar, Jayanta, Singh, Divya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577939/
https://www.ncbi.nlm.nih.gov/pubmed/36267566
http://dx.doi.org/10.3389/fendo.2022.977347