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Age alters the oncogenic trajectory toward luminal mammary tumors that activate unfolded proteins responses

A major limitation in the use of mouse models in breast cancer research is that most mice develop estrogen receptor‐alpha (ERα)‐negative mammary tumors, while in humans, the majority of breast cancers are ERα‐positive. Therefore, developing mouse models that best mimic the disease in humans is of fu...

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Detalles Bibliográficos
Autores principales: Jenkins, Edmund Charles, Chattopadhyay, Mrittika, Gomez, Maria, Torre, Denis, Ma'ayan, Avi, Torres‐Martin, Miguel, Sia, Daniela, Germain, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577951/
https://www.ncbi.nlm.nih.gov/pubmed/36111352
http://dx.doi.org/10.1111/acel.13665