Myeloid cell‐specific mutation of Spi1 selectively reduces M2‐biased macrophage numbers in skeletal muscle, reduces age‐related muscle fibrosis and prevents sarcopenia

Intramuscular macrophages play key regulatory roles in determining the response of skeletal muscle to injury and disease. Recent investigations showed that the numbers and phenotype of intramuscular macrophages change during aging, suggesting that those changes could influence the aging process. We...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Welc, Steven S., Wehling‐Henricks, Michelle, Kong, Ying, Thomas, Connor, Montecino‐Rodriguez, Enca, Dorshkind, Kenneth, Tidball, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577952/
https://www.ncbi.nlm.nih.gov/pubmed/36098370
http://dx.doi.org/10.1111/acel.13690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577952/
https://www.ncbi.nlm.nih.gov/pubmed/36098370
http://dx.doi.org/10.1111/acel.13690

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