The lysosomal proteome of senescent cells contributes to the senescence secretome

Senescent cells accumulate in tissues over time, favoring the onset and progression of multiple age‐related diseases. Senescent cells present a remarkable increase in lysosomal mass and elevated autophagic activity. Here, we report that two main autophagic pathways macroautophagy (MA) and chaperone‐...

Descripción completa

Detalles Bibliográficos
Autores principales: Rovira, Miguel, Sereda, Rebecca, Pladevall‐Morera, David, Ramponi, Valentina, Marin, Ines, Maus, Mate, Madrigal‐Matute, Julio, Díaz, Antonio, García, Fernando, Muñoz, Javier, Cuervo, Ana María, Serrano, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577959/
https://www.ncbi.nlm.nih.gov/pubmed/36087066
http://dx.doi.org/10.1111/acel.13707

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577959/
https://www.ncbi.nlm.nih.gov/pubmed/36087066
http://dx.doi.org/10.1111/acel.13707

Ejemplares similares