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The lysosomal proteome of senescent cells contributes to the senescence secretome

Senescent cells accumulate in tissues over time, favoring the onset and progression of multiple age‐related diseases. Senescent cells present a remarkable increase in lysosomal mass and elevated autophagic activity. Here, we report that two main autophagic pathways macroautophagy (MA) and chaperone‐...

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Detalles Bibliográficos
Autores principales:	Rovira, Miguel, Sereda, Rebecca, Pladevall‐Morera, David, Ramponi, Valentina, Marin, Ines, Maus, Mate, Madrigal‐Matute, Julio, Díaz, Antonio, García, Fernando, Muñoz, Javier, Cuervo, Ana María, Serrano, Manuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577959/ https://www.ncbi.nlm.nih.gov/pubmed/36087066 http://dx.doi.org/10.1111/acel.13707

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