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Design, synthesis, molecular modeling, and bioactivity evaluation of 1,10-phenanthroline and prodigiosin (Ps) derivatives and their Copper(I) complexes against mTOR and HDAC enzymes as highly potent and effective new anticancer therapeutic drugs

Breast cancer is the second type of cancer with a high probability of brain metastasis and has always been one of the main problems of breast cancer research due to the lack of effective treatment methods. Demand for developing an effective drug against breast cancer brain metastasis and finding mol...

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Detalles Bibliográficos
Autores principales: Cetin, M. Mustafa, Peng, Wenjing, Unruh, Daniel, Mayer, Michael F., Mechref, Yehia, Yelekci, Kemal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578020/
https://www.ncbi.nlm.nih.gov/pubmed/36267272
http://dx.doi.org/10.3389/fphar.2022.980479