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Single-Dose, Patient-Initiated Amenamevir Therapy for Recurrent Genital Herpes: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study

BACKGROUND: Amenamevir is a helicase-primase inhibitor with novel mechanisms of antiherpetic action. A patient-initiated single-dose regimen showed clinical efficacy for genital herpes in a phase 2 study. METHODS: In this phase 3 study, adult immunocompetent patients with recurrent genital herpes an...

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Detalles Bibliográficos
Autores principales: Kawashima, Makoto, Imafuku, Shinichi, Fujio, Kosuke, Komazaki, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578154/
https://www.ncbi.nlm.nih.gov/pubmed/36267254
http://dx.doi.org/10.1093/ofid/ofac494