The synthetic lethality of targeting cell cycle checkpoints and PARPs in cancer treatment

Continuous cell division is a hallmark of cancer, and the underlying mechanism is tumor genomics instability. Cell cycle checkpoints are critical for enabling an orderly cell cycle and maintaining genome stability during cell division. Based on their distinct functions in cell cycle control, cell cy...

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Detalles Bibliográficos
Autores principales: Li, Shuangying, Wang, Liangliang, Wang, Yuanyuan, Zhang, Changyi, Hong, Zhenya, Han, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578258/
https://www.ncbi.nlm.nih.gov/pubmed/36253861
http://dx.doi.org/10.1186/s13045-022-01360-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578258/
https://www.ncbi.nlm.nih.gov/pubmed/36253861
http://dx.doi.org/10.1186/s13045-022-01360-x

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