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Condensation of acrylonitrile and aryl acetonitrile: construction of α-amino-β-cyano cyclohexene skeletons

A representative condensation of acrylonitrile and aryl acetonitrile has been reported for the synthesis of α-amino-β-cyano cyclohexene. The reaction was carried out mildly in an open environment at room temperature. The scope and versatility of the method have been demonstrated with 20 examples, co...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Tang, Chuan-Su, Xiang, Shi-Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578340/
https://www.ncbi.nlm.nih.gov/pubmed/36321094
http://dx.doi.org/10.1039/d2ra04936h