Intrinsic Antibacterial Activity of Xeruborbactam In Vitro: Assessing Spectrum and Mode of Action

Xeruborbactam (formerly QPX7728) is a cyclic boronate inhibitor of numerous serine and metallo-beta-lactamases. At concentrations generally higher than those required for beta-lactamase inhibition, xeruborbactam has direct antibacterial activity against some Gram-negative bacteria, with MIC(50)/MIC(...

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Detalles Bibliográficos
Autores principales: Sun, Dongxu, Tsivkovski, Ruslan, Pogliano, Joe, Tsunemoto, Hannah, Nelson, Kirk, Rubio-Aparicio, Debora, Lomovskaya, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Mechanisms of Action: Physiological Effects
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578396/
https://www.ncbi.nlm.nih.gov/pubmed/36102663
http://dx.doi.org/10.1128/aac.00879-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578396/
https://www.ncbi.nlm.nih.gov/pubmed/36102663
http://dx.doi.org/10.1128/aac.00879-22

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